Complete the Self-Assessment Performance Review

Use this checklist to evaluate your current practices with patients who are at risk for heparin-induced thrombocytopenia (HIT). This can be used to review specific patient charts or as a guide to think about which components are currently implemented in your standard protocols for patients at risk for or undergoing treatment of HIT.

All fields required

Presentation

 
Platelet count at presentation (x 109/L)

 
150
100-150
50-100
20-50
< 20

 

 
Platelets with respect to baseline

 
80%
50-80%
30-50%
< 30%
 

 
Is there a known cause of thrombocytopenia?

 
Recent surgery or procedure  
Glycoprotein IIB-IIIA inhibitors  
Antibiotics  
Sepsis  
ITP  
MDS  
Chemotherapy  
None known
 

 
Current anticoagulants

 
UFH  
LMWH  
Fondaparinux  
Argatroban  
Lepirudin  
Bivalirudin  
Warfarin
 

 
If heparin was given recently, how long ago was it stopped?

 
> 100 days  
15-100 days  
5-14 days  
1-4 days  
Not stopped, current
 

 
Evidence of blood disorder

 
Bleeding  
Thrombosis  
Anemia  
Other
 

 
Other signs of thrombosis?

 
Skin Lesions?  Yes   No  
 
Acute systemic reactions following bolus?
Fever
Chills
Tachycardia
Dyspnea
Transient global amnesia
 

 
Heparin exposure?

 
Current  UFH   LMWH  
 
 
Prior       UFH   LMWH
 

"4T" Evaluator

 
Thrombocytopenia

 
> 50% fall, nadir ≥ 20 x 109/L
30-50% fall or nadir 10-19 x 109/L
< 30% fall or nadir < 10 x 109/L
 

 
Timing of platelet count fall consistent with HIT

 
Clear onset days 5-10 or ≤ day 1
       (recent heparin)
Possible
No (< day 4)
 

 
Thrombosis

 
Yes
Possible
No
 

 
Other causes of thrombocytopenia?

 
No
Possible
Likely
 

Confirmatory Tests

 
PF-4/heparin antibody test?

 
Positive
Negative
 

 
Serotonin release assay?

 
Positive
Negative
 

If HIT was diagnosis,

 
Which management steps did you take?

 
Stopped all heparins
Initiated alternative anticoagulant
       (not warfarin)
Transitioned to warfarin
 

 
What was the outcome?

 
Uneventful resolution of thrombocytopenia
Thrombosis
PE
Acute systemic reaction
Acute limb ischemia
Necrosis
Amputation
Stroke
MI
Death
 

 
Did this analysis influence your subsequent patient management?

 
Yes
No
 

 
Did this analysis influence your workplace practices?

 
Yes
No